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Product Name
LYN antibody
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Description
LYN Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Positive IHC detected in human placenta tissue. Observed molecular weight by Western-blot: 56kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
FLJ26625 antibody; JTK8 antibody; LYN antibody; Tyrosine protein kinase Lyn antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of LYN recombinant protein (Accession Number: NM_002350). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107409(LYN antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:107409(LYN Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human placenta tissue slide using Catalog No:107409(LYN Antibody) at dilution of 1:50 (under 40x lens)
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Background
LYN, also named as JTK8, p53Lyn and p56Lyn, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents. LYN is a component of the mTOR (mammalian target of rapamycin) pathway.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"