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Product Name
Human CD16b/FCGR3B (His Tag) recombinant protein
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Description
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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Protein name
Low affinity immunoglobulin gamma Fc region receptor III-B
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Protein short names
RP11-25K21.3; CD16B
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Uniprot ID
O75015
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Gene Name
FCGR3B; CD16B; FCG3; FCGR3; IGFR3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD16b (NP_000561.3) (Met 1-Ser 200) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD16b comprises 195 amino acids with a predicted molecular mass of 22.2 kDa. As a result of glycosylation, rh CD16b migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CD16b / FCGR3B Protein (His Tag) SDS-PAGE
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