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Product Name
Human FCGR3B/CD16B/FCG3/FCGR3/IGFR3 (Fc & His tag) recombinant protein
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Description
Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
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Protein name
Fc fragment of IgG receptor IIIb(FCGR3B)
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Protein short names
CD16B; FCG3; FCGR3; IGFR3
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Uniprot ID
O75015
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FCGR3B/CD16B/FCG3/FCGR3/IGFR3 Thr20-Gln208 is expressed with a Fc, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FCGR3B/CD16B/FCG3/FCGR3/IGFR3 (Fc & His tag) recombinant protein
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