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  • Anti-FCGR3 antibody

Anti-FCGR3 antibody

Cat.#: 142192

Special Price 80.6 USD

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Product Information

  • Product Name
    Anti-FCGR3 antibody
  • Documents
  • Description
    Mouse Monoclonal to Human FCGR3
  • Tested applications
    FCM
  • Species reactivity
    Human CD16 (CD16a & CD16b)
  • Alternative names
    Fc gamma RIII antibody; CD16-2 antibody; CD16 antibody; CD16 antibody; Fc &gamma antibody; Fc gamma RIII antibody; FCG3 antibody; FcgammaRIV antibody; FCGR3 antibody; Fcgr3 antibody; Fcgr3a antibody; FCGR3A antibody; Fcgr4 antibody; FCGRIII antibody; FcgRIV antibody; FCR-10 antibody; FCRIII antibody; FcRIII antibody; FCRIIIA antibody; FCRIIIB antibody; IGFR3 antibody; RIII antibody
  • Immunogen
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16b/Fc gamma RIIIb and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
  • Clonality
    Monoclonal
  • Formulation
    Aqueous solution containing 0.5% BSA and 0.09% sodium azide
  • Storage instructions
    This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
    Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
  • Applications
    FCM
  • Validations

    Human CD16/Fc gamma RIII Flow Cytometry (FC) 15919

    Human CD16/Fc gamma RIII Flow Cytometry (FC) 15919

  • Background
    Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"