Anti-FCGR3 antibody

Anti-FCGR3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Monoclonal to Human FCGR3

FCM

Human CD16 (CD16a & CD16b)

Fc gamma RIII antibody; CD16-2 antibody; CD16 antibody; CD16 antibody; Fc &gamma antibody; Fc gamma RIII antibody; FCG3 antibody; FcgammaRIV antibody; FCGR3 antibody; Fcgr3 antibody; Fcgr3a antibody; FCGR3A antibody; Fcgr4 antibody; FCGRIII antibody; FcgRIV antibody; FCR-10 antibody; FCRIII antibody; FcRIII antibody; FCRIIIA antibody; FCRIIIB antibody; IGFR3 antibody; RIII antibody

Mouse IgG1

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16b/Fc gamma RIIIb and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.