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  • Human ILT6 / LILRA3 (Fc Tag) recombinant protein

Human ILT6 / LILRA3 (Fc Tag) recombinant protein

Cat.#: 502813

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Product Information

  • Product Name
    Human ILT6 / LILRA3 (Fc Tag) recombinant protein
  • Documents
  • Description
    Acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
  • Protein name
    Leukocyte immunoglobulin-like receptor subfamily A member 3
  • Protein short names
    LIR4; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR SUBFAMILY A MEMBER 3; IMMUNOGLOBULIN-LIKE TRANSCRIPT 6; ILT6 / LILRA3; XXBAC-BCX403H19.1; HM43; CD85 ANTIGEN-LIKE FAMILY MEMBER E; MONOCYTE INHIBITORY RECEPTOR HM43/HM31; E3; LEUCOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR; LIR-4; HM31; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR A3; CD85E; LEUKOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR 4; ILT-6
  • Uniprot ID
    Q8N6C8
  • Gene Name
    LILRA3; ILT6; LIR4
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human LILRA3 (AAH28208.1) (Met1-Glu439) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human LILRA3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 657 amino acids and has a predicted molecular mass of 72 kDa. The apparent molecular mass of the protein is approximately 102 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 80 % as determined by SDS-PAGE
  • Validations

    Human ILT6 / LILRA3 Protein (Fc Tag) SDS-PAGE

    Human ILT6 / LILRA3 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"