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Product Name
Human MESDC2 (His Tag) recombinant protein
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Description
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
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Protein name
LDLR chaperone MESD
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Protein short names
MSD; MESDC2; 2210015O11RIK; MESD; BOCA; UNQ1911/PRO4369; MGC25959; AW537813; MKIAA0081; KIAA0081
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Uniprot ID
Q14696
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Gene Name
MESDC2; KIAA0081; MESD; UNQ1911/PRO4369
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MESDC2 (NP_055969.1) (Ala 34-Lys 230) was fused with a signal peptide at the N-terminus and a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human MESDC2 consists of 208 amino acids and has a predicted molecular mass of 23.6 kDa. The apparent molecular mass of rh MESDC2 is approximately 27 kDa in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human MESDC2 / MESD Protein (His Tag) SDS-PAGE
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