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Product Name
LCK antibody
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Description
LCK Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 56 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
LCK antibody; LSK antibody; p56 LCK antibody; p56lck antibody; pp58lck antibody; Protein YT16 antibody; Proto oncogene Lck antibody; Tyrosine protein kinase Lck antibody; YT16 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of LCK recombinant protein (Accession Number: BC013200). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:112172(LCK antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:112172(LCK antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:112172(LCK antibody) at dilution of 1:100 (under 40x lens)
IP Result of anti-LCK (IP:Catalog No:112172, 4ug; Detection:Catalog No:112172 1:500) with Jurkat cells lysate 4000ug.
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Background
LCK(Lymphocyte cell-specific protein-tyrosine kinase) is also named as LSK,p56-LCK and a nonreceptor protein-tyrosine kinase of the SRConcogene family that is involved in transduction of T-cell receptor-mediated activation.It is implicated in the control of lymphocyte growth by virtue of its overexpression in some lymphoid malignancies and its transforming activity in heterologous systems(PMID:2784463).It has 3 isoforms produced by alternative splicing.
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