LBR Polyclonal Antibody
Polyclonal antibody to LBR
WB, IHC, IF
Human, Mouse, Rat
LBR antibody; DHCR14B antibody; LMN2R antibody; PHA antibody; TDRD18 antibody; lamin-B receptor antibody
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR (NP_002287.2).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Western blot - LBR Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using LBR antibody at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 90s.
Immunohistochemistry - LBR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using LBR antibody at dilution of 1:200 (40x lens).
Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation (By similarity). Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation (By similarity). Anchors the lamina and the heterochromatin to the inner nuclear membrane.
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