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Product Name
Cynomolgus CD62L/L-Selectin (Fc Tag) recombinant protein
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Description
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (By similarity).
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Protein name
L-selectin
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Protein short names
LY-M22; LNHR; LEU8; CD62L; LSEL; LAM1; AI528707; LY-22; LECAM-1; L-SELECTIN; PLNHR; TQ1; LYAM-1; LECAM1; LYAM1; SELL
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Uniprot ID
Q95198
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Gene Name
SELL
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the cynomolgus SELL (Q95198) (Met1-Asn332) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Cynomolgus
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Molecular weight
The recombinant cynomolgus SELL is a disulfide-linked homodimer. The reduced monomer comprises 545 amino acids and has a calculated molecular mass of 61.1 KDa. The apparent molecular mass of the protein is approximately 85 and 35 KDa respectively in SDS-PAGE.
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Purity
(70.4+19.8) % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.
When 5 x 10E4 cells/well are added to cyno L-Selectin coated plates (10 μg/mL with 100 μL/well), > 50% cells will adhere for 1 hour incubation at 37℃. -
Validations
Cynomolgus CD62L / L-Selectin / SELL Protein (Fc Tag) SDS-PAGE
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