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Product Name
Human CD62L/L-Selectin (His Tag) recombinant protein
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Description
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
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Protein name
L-selectin
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Protein short names
L-SELECTIN; LECAM-1; TQ1; PLNHR; LYAM1; LECAM1; LYAM-1; SELL; LEU8; LNHR; LY-M22; CD62L; LSEL; AI528707; LY-22; LAM1
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Uniprot ID
P14151
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Gene Name
SELL; LNHR; LYAM1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SELL (P14151-1) extracellular domain (Met 1-Asn 332) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human SELL consists of 305 amino acids and predictes a molecular mass of 34.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhSELL is approximately 55-65 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind biotinylated human CD34 in a functional ELISA.
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Validations
Human CD62L / L-Selectin / SELL Protein (His Tag) SDS-PAGE
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