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Product Name
KLF12 antibody
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Description
KLF12 Rabbit Polyclonal antibody. Positive WB detected in Raji cells, HepG2 cells, human kidney tissue. Observed molecular weight by Western-blot: 65 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AP 2rep antibody; AP2REP antibody; HSPC122 antibody; KLF12 antibody; Krueppel like factor 12 antibody; Kruppel like factor 12 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of KLF12 recombinant protein (Accession Number: NM_001400139). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
Raji cells were subjected to SDS PAGE followed by western blot with Catalog No:112077(KLF12 antibody) at dilution of 1:400
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Background
KLF12, also named as AP2REP or HSPC122, is a 402 amino acid protein, which contains three C2H2-type zinc fingers and belongs to the Sp1 C2H2-type zinc-finger protein family. KLF12 localizes in the nucleus and confers strong transcriptional repression to the AP-2-alpha gene. KLF12 is atranscriptional silencer to the AP2-alpha gene, mediating positive and negative regulation of the AP2-A expression trhough a set of overlapping cis-regulatory promoters elements.
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References
- Shen X, Hu Y, Jiang Y. Krüppel-like factor 12 negatively regulates human endometrial stromal cell decidualization. Biochemical and biophysical research communications. 433(1):11-7. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"