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KIF20A antibody

Cat.#: 112006

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Product Information

  • Product Name
    KIF20A antibody
  • Documents
  • Description
    KIF20A Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells, HL-60 cells. Observed molecular weight by Western-blot: 100 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    FLJ21151 antibody; GG10_2 antibody; KIF20A antibody; kinesin family member 20A antibody; Kinesin like protein KIF20A antibody; MKLP2 antibody; RAB6KIFL antibody; Rabkinesin 6 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of KIF20A recombinant protein (Accession Number: NM_005733). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:112006(KIF20A antibody) at dilution of 1:500

    HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:112006(KIF20A antibody) at dilution of 1:500

    IP Result of anti-KIF20A (IP:Catalog No:112006, 4ug; Detection:Catalog No:112006 1:500) with HEK-293 cells lysate 1200ug.

    IP Result of anti-KIF20A (IP:Catalog No:112006, 4ug; Detection:Catalog No:112006 1:500) with HEK-293 cells lysate 1200ug.

  • Background
    KIF20A, also known as RAB6KIFL or MKlp2, is a kinesin originally identified as a binding partner for the rab6 GTPase involved in protein transport at the Golgi apparatus. KIF20A belongs to a large family of motor proteins that accumulate in mitotic cells and is required for normal cell division. KIF20A is thought to be involved in carcinogenesis. In normal tissues KIF20A is almost undetectable while it is overexpressed in various cancers. KIF20A has been identified as a novel promising candidate for anticancer immunotherapy.
  • References
    • Yan GR, Zou FY, Dang BL. Genistein-induced mitotic arrest of gastric cancer cells by downregulating KIF20A, a proteomics study. Proteomics. 12(14):2391-9. 2012.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"