JP45/JSRP1 antibody

Cat.#: 111895

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Product Information

  • Product Name
    JP45/JSRP1 antibody
  • Documents
  • Description
    JP45/JSRP1 Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue. Positive WB detected in human skeletal muscle tissue. Observed molecular weight by Western-blot: 30kd
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    FLJ32416 antibody; JP 45 antibody; JP45 antibody; JP45/JSRP1 antibody; JSRP1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of JP45/JSRP1 recombinant protein (Accession Number: NM_144616). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111895(JP45; JSRP1 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:111895(JP45; JSRP1 antibody) at dilution of 1:50 (under 10x lens)

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111895(JP45; JSRP1 Antibody) at dilution of 1:600

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111895(JP45; JSRP1 Antibody) at dilution of 1:600

  • Background
    JSRP1 (Junctional sarcoplasmic reticulum protein 1), also known as JP-45, is an integral protein of the junctional face membrane of the skeletal muscle sarcoplasmic reticulum (SR), and interacts with calsequestrin and the skeletal-muscle dihydropyridine receptor Cav1. JP-45 is an important protein for functional expression of voltage-dependent calcium channels. Involvement of JP-45 in the molecular mechanism underlying skeletal muscle excitation-contraction coupling has been reported. Although the predicated molecular weight of JP-45 is 36 kDa, it appears a 45-kDa band in western blotting in most cases.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"