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Product Name
iPLA2 antibody
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Description
iPLA2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Positive IP detected in mouse testis tissue. Positive IHC detected in human small intestine tissue, human brain tissue. Observed molecular weight by Western-blot: 80 kDa,88 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CaI PLA2 antibody; Group VI phospholipase A2 antibody; GVI antibody; GVI PLA2 antibody; INAD1 antibody; iPLA2 antibody; IPLA2 VIA antibody; PARK14 antibody; PLA2 antibody; PLA2G6 antibody; PNPLA9 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of iPLA2 recombinant protein (Accession Number: XM_005261764). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:111817(PLA2G6 antibody) at dilution of 1:1000
IP Result of anti-PLA2G6 (IP:Catalog No:111817, 4ug; Detection:Catalog No:111817 1:800) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:111817(PLA2G6 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:111817(PLA2G6 Antibody) at dilution of 1:50 (under 40x lens)
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Background
PLA2G6, also named as PLPLA9, is involved in the remodeling of membranes allowing arachidonic acid to be placed in the proper position in phospholipids for stimulated release. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. This protein has 4 isoforms produced by alternative splicing.
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