-
Product Name
Human PLA2G6 Recombinant protein (His tag)
- Documents
-
Description
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.; Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
-
Protein name
85/88 kDa calcium-independent phospholipase A2
-
Protein short names
PLPLA9
-
Uniprot ID
A0A590UK51
-
Gene Name
PLA2G6; PLPLA9
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human PLA2G6 (NP_003551.2) 1-343 aa was fused with the polyhistidine tag
-
Protein Species
Human
-
Activity
Not tested.
-
Validations
Recombinant human PLA2G6 SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"