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Product Name
Mouse IL7 / interleukin-7 recombinant protein
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Description
Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.
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Protein name
Interleukin-7
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Protein short names
A630026I06RIK; IL-7; INTERLEUKIN 7; HLB368; IL7
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Uniprot ID
Q544C8
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Gene Name
Il7; Il-7
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse IL7 (NP_032397.1) (Glu26-Ile154) was expressed and purified with an initial Met.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse IL7 consists of 130 amino acids and predicts a molecular mass of 15 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured in a cell proliferation assay using antibody against CD3-activated human peripheral blood lymphocytes (PBL).
The ED50 for this effect is typically 1.3-5.2 ng/mL. -
Validations
Mouse IL7 / Interleukin 7 Protein SDS-PAGE
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