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Product Name
Mouse IL-1R8/IL1RAPL1 (Fc Tag) recombinant protein
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Description
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in presynaptic and postsynaptic differentiation and dendritic spine formation in neurons.
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Protein name
Interleukin-1 receptor accessory protein-like 1
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Protein short names
6330532G10RIK; RP23-301L16.1; IL1RAPL; IL-1R8; MRX34; TIGIRR-2; OPHN4; IL1RAPL1; MRX10; IL1R8; C030039N24; MRX21
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Uniprot ID
P59823
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Gene Name
Il1rapl1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse IL1RAPL1 (P59823) extracellular domain (Met 1-Thr 357) was fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse IL1RAPL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 574 amino acids and has a calculated molecular mass of 65 kDa. As a result of glycosylation, the apparent molecular mass of rmIL1RAPL1/Fc monomer is approximately 85-95 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse IL-1R8 / IL1RAPL1 Protein (Fc Tag) SDS-PAGE
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