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Product Name
Integrin alpha 6X1B-Specific antibody
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Description
Integrin alpha 6X1B-Specific Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, mouse kidney tissue. Observed molecular weight by Western-blot: 62 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CD49f antibody; DKFZp686J01244 antibody; FLJ18737 antibody; Integrin alpha 6 antibody; integrin antibody; alpha 6 antibody; ITGA6 antibody; ITGA6B antibody; VLA 6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001079818). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:111856(ITGA6-Specific antibody) at dilution of 1:300
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Background
ITGA6, also named asITGA6B, CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. This antibody is specific to isoform Alpha-6X1X2B, isoform Alpha-6X1B and isoform Alpha-6X2B.
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