IL-16 Mouse Monoclonal antibody. Positive WB detected in Recombinant protein. Observed molecular weight by Western-blot: 37 kDa
Human; other species not tested.
FLJ16806 antibody; FLJ42735 antibody; FLJ44234 antibody; HsT19289 antibody; IL 16 antibody; IL16 antibody; LCF antibody; prIL 16 antibody; Pro interleukin 16 antibody
This antibody was obtained by immunization of IL-16 recombinant protein (Accession Number: BC040272). Purification method: Protein A purified.
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20℃. DO NOT ALIQUOT
Recombinant protein were subjected to SDS PAGE followed by western blot with Catalog No:107381(IL16 antibody) at dilution of 1:20000
IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.
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