IKIP antibody

Cat.#: 111646

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Product Information

  • Product Name
    IKIP antibody
  • Documents
  • Description
    IKIP Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue, mouse spleen tissue, mouse thymus tissue. Observed molecular weight by Western-blot: 40kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    FLJ31051 antibody; IKBIP antibody; IKBKB interacting protein antibody; IKIP antibody; IKK interacting protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of IKIP recombinant protein (Accession Number: NM_153687). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111646(IKIP antibody) at dilution of 1:500

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111646(IKIP antibody) at dilution of 1:500

  • Background
    IKIP(Inhibitor of nuclear factor kappa-B kinase-interacting protein) is also named as IKBIP and acts as a novel p53 target gene with proapoptotic function. A variety of experiments looking at endogenous IKIP1 levels showed that IKIP1 expression is dependent on p53. Transfection of IKIP into endothelial cells promotes cell death, as measured by TUNEL staining. EST analysis and RT-PCR demonstrated that 3 IKIP transcripts are generated; IKIP1 encodes a 377-amino acid protein, IKIP2 a 350-amino acid protein, and IKIP3 2 potential ORFs encoding 70- and 245-amino acid proteins(PMID:15389287).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"