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Product Name
IKIP antibody
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Description
IKIP Rabbit Polyclonal antibody. Positive WB detected in mouse skeletal muscle tissue, mouse spleen tissue, mouse thymus tissue. Observed molecular weight by Western-blot: 40kd
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
FLJ31051 antibody; IKBIP antibody; IKBKB interacting protein antibody; IKIP antibody; IKK interacting protein antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IKIP recombinant protein (Accession Number: NM_153687). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:111646(IKIP antibody) at dilution of 1:500
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Background
IKIP(Inhibitor of nuclear factor kappa-B kinase-interacting protein) is also named as IKBIP and acts as a novel p53 target gene with proapoptotic function. A variety of experiments looking at endogenous IKIP1 levels showed that IKIP1 expression is dependent on p53. Transfection of IKIP into endothelial cells promotes cell death, as measured by TUNEL staining. EST analysis and RT-PCR demonstrated that 3 IKIP transcripts are generated; IKIP1 encodes a 377-amino acid protein, IKIP2 a 350-amino acid protein, and IKIP3 2 potential ORFs encoding 70- and 245-amino acid proteins(PMID:15389287).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"