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Product Name
IFIT5 antibody
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Description
IFIT5 Rabbit Polyclonal antibody. Positive IP detected in A375 cells. Positive WB detected in A375 cells, PC-3 cells. Positive IHC detected in human skin cancer tissue. Observed molecular weight by Western-blot: 56-58 kDa,48 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human; other species not tested.
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Alternative names
FLJ53857 antibody; FLJ92678 antibody; IFIT 5 antibody; IFIT5 antibody; RI58 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IFIT5 recombinant protein (Accession Number: NM_012420). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
A375 cells were subjected to SDS PAGE followed by western blot with Catalog No:111621(IFIT5 antibody) at dilution of 1:200
IP Result of anti-IFIT5 (IP:Catalog No:111621, 4ug; Detection:Catalog No:111621 1:300) with A375 cells lysate 2200ug.
Immunohistochemistry of paraffin-embedded human skin cancer tissue slide using Catalog No:111621(IFIT5 Antibody) at dilution of 1:50 (under 40x lens)
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Background
IFIT5, also named as Interferon-induced 58 kDa protein or RI58, is a 482 amino acid protein, which contains eight TPR repeats and belongs to the IFIT family. IFIT5 localizes in the Cell projection. Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs.
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References
- Zhang B, Liu X, Chen W, Chen L. IFIT5 potentiates anti-viral response through enhancing innate immune signaling pathways. Acta biochimica et biophysica Sinica. 45(10):867-74. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"