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Product Name
IFIT1 antibody
- Documents
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Description
IFIT1 Rabbit Polyclonal antibody. Positive IHC detected in human breast cancer, human liver cancer. Positive WB detected in U-937 cells, HeLa cells, LPS treated RAW 264.7 cells. Observed molecular weight by Western-blot: 55 Kda
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
G10P1 antibody; GARG 16 antibody; IFI 56 antibody; IFI 56K antibody; IFI56 antibody; IFIT 1 antibody; IFIT1 antibody; IFNAI1 antibody; ISG56 antibody; RNM561 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IFIT1 recombinant protein (Accession Number: NM_001548). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:111617(IFIT1 Antibody) at dilution of 1:600
LPS treated RAW 264.7 cells were subjected to SDS PAGE followed by western blot with Catalog No:111617(IFIT1 Antibody) at dilution of 1:600
U-937 cells were subjected to SDS PAGE followed by western blot with Catalog No:111617(IFIT1 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:111617(IFIT1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:111617(IFIT1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human liver cancer slide using Catalog No:111617(IFIT1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human liver cancer slide using Catalog No:111617(IFIT1 Antibody) at dilution of 1:50
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Background
IFIT1 is, also known as glucocorticoid-attenuated response gene 16 protein (GARG-16), is a 463 amino acid protein belonging to the IFIT family. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFIT1 specifically bound virus PPP-RNA forms a complex with IFIT2 and IFIT3 to sequester the viral PPP-RNA and prevent virus replication.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"