HYAL4 antibody

HYAL4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

HYAL4 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in mouse testis tissue, NIH/3T3 cells. Positive IHC detected in human testis tissue, human placenta tissue. Observed molecular weight by Western-blot: 65 kDa

ELISA, IHC, WB, IP

Human,Mouse,Rat; other species not tested.

Hyal 4 antibody; HYAL4 antibody; Hyaluronidase 4 antibody; hyaluronoglucosaminidase 4 antibody

Rabbit IgG

This antibody was obtained by immunization of HYAL4 recombinant protein (Accession Number: XM_017011911). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Hyaluronic acid (HA), a glycosaminoglycan that is ubiquitously present in the extracellular space of higher animals, maintains matrix structure and controls cellular functions such as proliferation, differentiation, and locomotion. Hyaluronidases, enzymes that catabolize HA, are involved in development and tumorigenesis. Hyaluronidase-4 (HYAL4), a member of the hyaluronidase family, is a chondroitin sulfate (CS)-specific endo-β-N-acetylgalactosaminidase. The expression of hHYAL4 mRNA is not ubiquitous but restricted to placenta, skeletal muscle, and testis (PMID: 23086929). This polyclonal antibody raised against 29-460aa of human HYAL4. The apparent molecular weight is larger than the calculated molecular weight of 54 kDa, which is likely due to posttranslational modification, presumably by glycosylation (PMID: 19889881).