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Product Name
Human ZNF238 Recombinant protein (GST tag)
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Description
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. {PubMed:9756912}.
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Protein name
Zinc finger and BTB domain-containing protein 18
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Protein short names
RP58; TAZ1; ZNF238
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Uniprot ID
Q99592
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Gene Name
ZBTB18; RP58; TAZ1; ZNF238
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human ZBTB18 (NP_991331.1) 323-522 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human ZNF238 SDS-PAGE
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