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Product Name
Human UBE2T/HSPC150/PIG50 (His tag) recombinant protein
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Description
Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.
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Protein name
ubiquitin conjugating enzyme E2 T(UBE2T)
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Protein short names
HSPC150; PIG50
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Uniprot ID
Q9NPD8
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human UBE2T/HSPC150/PIG50 Met1-Val197 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human UBE2T/HSPC150/PIG50 (His tag) recombinant protein
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