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Product Name
Human TRPV5 Recombinant protein (His tag)
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Description
Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity). {, PubMed:11549322}.
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Protein name
Transient receptor potential cation channel subfamily V member 5
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Protein short names
ECAC1
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Uniprot ID
Q9NQA5
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Gene Name
TRPV5; ECAC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TRPV5 (NP_062815.3) 1-331 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TRPV5 SDS-PAGE
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