Human TNFRSF21/DR6/UNQ437/PRO868 (Fc tag) recombinant protein

Cat.#: 519397

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Product Information

  • Product Name
    Human TNFRSF21/DR6/UNQ437/PRO868 (Fc tag) recombinant protein
  • Documents
  • Description
    Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF-α.
  • Protein name
    TNF receptor superfamily member 21(TNFRSF21)
  • Protein short names
    DR6; UNQ437; PRO868
  • Uniprot ID
    O75509
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TNFRSF21/DR6/UNQ437/PRO868 Gln42-Leu350 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TNFRSF21/DR6/UNQ437/PRO868 (Fc tag) recombinant protein

    Human TNFRSF21/DR6/UNQ437/PRO868 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"