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Product Name
Human THPO/MGDF (His tag) recombinant protein
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Description
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
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Protein name
thrombopoietin(THPO)
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Protein short names
MGDF
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Uniprot ID
P40225
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human THPO/MGDF Ser22-Gly353 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human THPO/MGDF (His tag) recombinant protein
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