Human THOC7 Recombinant protein (GST tag)

Cat.#: 513557

Size:

Special Price 294.7 USD

Availability: 2-3 weeks
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human THOC7 Recombinant protein (GST tag)
  • Documents
  • Description
    Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. {PubMed:15833825, PubMed:15998806, PubMed:17190602, PubMed:23222130}.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. {PubMed:18974867}.
  • Protein name
    THO complex subunit 7 homolog
  • Protein short names
    NIF3L1BP1
  • Uniprot ID
    Q6I9Y2
  • Gene Name
    THOC7; NIF3L1BP1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human THOC7 (NP_079351.2) 1-204 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human THOC7(Full length) SDS-PAGE

    Recombinant human THOC7(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"