Human STIM2 Recombinant protein (His tag)

Cat.#: 513210

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Product Information

  • Product Name
    Human STIM2 Recombinant protein (His tag)
  • Documents
  • Description
    Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. {PubMed:16005298, PubMed:16860747, PubMed:17905723, PubMed:18160041, PubMed:21217057, PubMed:22464749, PubMed:23359669}.
  • Protein name
    Stromal interaction molecule 2
  • Protein short names
    KIAA1482
  • Uniprot ID
    Q9P246
  • Gene Name
    STIM2; KIAA1482
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human STIM2 (NP_001162589.1) 446-595 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human STIM2 SDS-PAGE

    Recombinant human STIM2 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"