Human S100A8/S100A9 Heterodimer (His tag) recombinant protein

Cat.#: 518826

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Product Information

  • Product Name
    Human S100A8/S100A9 Heterodimer (His tag) recombinant protein
  • Documents
  • Description
    S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
  • Protein name
    S100 Calcium Binding Protein A8/A9 Heterodimer
  • Protein short names
    S100A9 Heterodimer
  • Uniprot ID
    P05109 & P06702
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human S100A8/S100A9 Heterodimer Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human S100A8/S100A9 Heterodimer (His tag) recombinant protein

    Human S100A8/S100A9 Heterodimer (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"