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Human QKI Recombinant protein (GST tag)

Cat.#: 511712

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Product Information

  • Product Name
    Human QKI Recombinant protein (GST tag)
  • Documents
  • Description
    RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). {UniProtKB:Q9QYS9, PubMed:16641098, PubMed:23630077}.
  • Protein name
    Protein quaking
  • Protein short names
    HKQ
  • Uniprot ID
    Q96PU8
  • Gene Name
    QKI; HKQ
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human QKI (NP_006766.1) 1-341 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human QKI(Full length) SDS-PAGE

    Recombinant human QKI(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"