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Human PPM1D Recombinant protein (His tag)

Cat.#: 511494

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human PPM1D Recombinant protein (His tag)
  • Documents
  • Description
    Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins. Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629). {PubMed:15870257, PubMed:16311512, PubMed:21283629}.
  • Protein name
    Protein phosphatase 1D
  • Protein short names
    WIP1
  • Uniprot ID
    A0A8J9C7E3
  • Gene Name
    PPM1D; WIP1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PPM1D (NP_003611.1) 254-423 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human PPM1D SDS-PAGE

    Recombinant human PPM1D SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"