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Product Name
Human PMVK/PMKI (His tag) recombinant protein
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Description
Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.
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Protein name
phosphomevalonate kinase(PMVK)
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Protein short names
PMKI
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Uniprot ID
Q15126
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PMVK/PMKI Met1-Leu192 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PMVK/PMKI (His tag) recombinant protein
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