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Product Name
Human PFN1 Recombinant protein (GST tag)
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Description
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. {PubMed:18573880}.
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Protein name
Profilin-1
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Uniprot ID
P07737
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Gene Name
PFN1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PFN1 (NP_005013.1) 1-140 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human PFN1(Full length) SDS-PAGE
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