Human Perforin Recombinant protein (His tag)

Cat.#: 511064

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Special Price 294.7 USD

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Product Information

  • Product Name
    Human Perforin Recombinant protein (His tag)
  • Documents
  • Description
    Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g. in transplant rejection or some forms of autoimmune disease. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes. {PubMed:20038786, PubMed:20225066, PubMed:20889983, PubMed:21037563, PubMed:9058810, PubMed:9164947}.
  • Protein name
    Perforin-1
  • Protein short names
    PFP
  • Uniprot ID
    P14222
  • Gene Name
    PRF1; PFP
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PRF1 (NP_005032.2) 247-555 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human Perforin SDS-PAGE

    Recombinant human Perforin SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"