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Product Name
Human PDCD1LG2/B7DC/CD273/PDCD1L2/PDL2 (His tag) recombinant protein
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Description
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
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Protein name
programmed cell death 1 ligand 2(PDCD1LG2)
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Protein short names
B7DC; CD273; PDCD1L2; PDL2
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Uniprot ID
Q9BQ51
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PDCD1LG2/B7DC/CD273/PDCD1L2/PDL2 Leu20-Pro219 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PDCD1LG2/B7DC/CD273/PDCD1L2/PDL2 (His tag) recombinant protein
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