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Product Name
Human NLRX1 Recombinant protein (His tag)
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Description
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313). {PubMed:18200010, PubMed:18219313}.
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Protein name
NLR family member X1
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Protein short names
NOD26; NOD5; NOD9
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Uniprot ID
Q86UT6
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Gene Name
NLRX1; NOD26; NOD5; NOD9
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NLRX1 (XP_054225923.1) 572-921 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NLRX1 SDS-PAGE
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