Human NECTIN4/LNIR/PRR4/PVRL4 (His tag) recombinant protein

Human NECTIN4/LNIR/PRR4/PVRL4 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

nectin cell adhesion molecule 4(NECTIN4)

LNIR; PRR4; PVRL4

Q96NY8

Human Cells

A DNA sequence encoding the Human NECTIN4/LNIR/PRR4/PVRL4 Gly31-Val351 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.