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Human NBL1/DAND1 (His Tag) recombinant protein

Cat.#: 504542

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Product Information

  • Product Name
    Human NBL1/DAND1 (His Tag) recombinant protein
  • Documents
  • Description
    Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
  • Protein name
    Neuroblastoma suppressor of tumorigenicity 1
  • Protein short names
    DAN; DAND1
  • Uniprot ID
    P41271
  • Gene Name
    NBL1; DAN; DAND1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DAN precursor (NP_005371.1) (Met 1-Asp 180) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human DAN consists of 176 amino acids and has a calculated molecular mass of 19.3 kDa. As a result of glycosylation, rh DAN migrates as an approximately 27 kDa protein in SDS-PAGE under reducing conditions.
  • Purity
    > 98 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 5-20 μg/ml in the presence of 50 ng/mL of recombinant human BMP4.
  • Validations

    Human NBL1 / DAND1 / DAN Protein (His Tag) SDS-PAGE

    Human NBL1 / DAND1 / DAN Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"