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Product Name
Human NANOS3 Recombinant protein (GST tag)
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Description
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. {PubMed:21421998}.
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Protein name
Nanos homolog 3
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Protein short names
NOS3
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Uniprot ID
P60323
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Gene Name
NANOS3; NOS3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NANOS3 (NP_001092092.1) 1-192 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NANOS3 SDS-PAGE
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