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Product Name
Human MVP Recombinant protein (His tag)
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Description
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases. {PubMed:15133037, PubMed:16418217, PubMed:16441665}.
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Protein name
Major vault protein
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Protein short names
LRP
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Uniprot ID
Q14764
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Gene Name
MVP; LRP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human MVP (NP_001280134.1) 480-827 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human MVP SDS-PAGE
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