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Human METAP1 (His Tag) recombinant protein

Cat.#: 504051

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Product Information

  • Product Name
    Human METAP1 (His Tag) recombinant protein
  • Documents
  • Description
    Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
  • Protein name
    Methionine aminopeptidase 1
  • Protein short names
    MKIAA0094; METHIONYL AMINOPEPTIDASE 1; MAP1A; METAP1; METAP1A; KIAA0094; 1700029C17RIK; AW047992; DKFZP781C0419
  • Uniprot ID
    P53582
  • Gene Name
    METAP1; KIAA0094
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human METAP1 (NP_055958.2) (His52-Phe386) was expressed with a polyhistidine tag at the C-terminus and an initial Met at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human METAP1 consists 347 amino acids and predicts a molecular mass of 39.3 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Human METAP1 Protein (His Tag)

    Human METAP1 Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"