Anti-METAP1 antibody

Anti-METAP1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to METAP1

ELISA, WB, IP

Human METAP1

MAP1A antibody; MetAP1A antibody; AW047992 antibody; mKIAA0094 antibody; 1700029C17Rik antibody; 1700029C17Rik antibody; AW047992 antibody; DKFZp781C0419 antibody; KIAA0094 antibody; KIAA0094 antibody; METAP1 antibody; METAP1 antibody; Methionyl Aminopeptidase 1 antibody; Methionyl Aminopeptidase 1 antibody; mKIAA0094 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human METAP1 (rh METAP1 ; NP_055958.2; His52-Phe386). METAP1 specific IgG was purified by Human METAP1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.