Human LIG3 Recombinant protein (His tag)

Cat.#: 509520

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Product Information

  • Product Name
    Human LIG3 Recombinant protein (His tag)
  • Documents
  • Description
    Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627). {PubMed:10207110, PubMed:24674627}.
  • Protein name
    DNA ligase 3
  • Uniprot ID
    P49916
  • Gene Name
    LIG3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    254-390 aa encoded by NM_013975 was inserted into PET30a vector
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human LIG3 SDS-PAGE

    Recombinant human LIG3 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"