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Product Name
Human LAS1L Recombinant protein (His tag)
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Description
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {PubMed:20647540, PubMed:22872859}.
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Protein name
Ribosomal biogenesis protein LAS1L
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Uniprot ID
Q9Y4W2
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Gene Name
LAS1L; MSTP060
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human LAS1L (NP_112483.1) 1-353 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human LAS1L SDS-PAGE
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