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Product Name
Human LAMR1,RPSA Recombinant protein (His tag)
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Description
Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. {HAMAP-Rule:MF_03016, PubMed:16263087, PubMed:6300843}.; (Microbial infection) Acts as a receptor for the adeno-associated viruses 2,3,8 and 9, dengue virus, Sindbis virus and Venezuelan equine encephalitis virus (PubMed:1385835, PubMed:15507651, PubMed:16973587). Also acts as a receptor for pathogenic prion protein and bacteria (PubMed:9396609, PubMed:11689427, PubMed:15516338). {PubMed:11689427, PubMed:1385835, PubMed:15507651, PubMed:15516338, PubMed:16973587, PubMed:9396609}.
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Protein name
40S ribosomal protein SA
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Protein short names
LAMBR; LAMR1
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Uniprot ID
P08865
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Gene Name
RPSA; LAMBR; LAMR1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RPSA (NP_002286.2) 1-295 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human LAMR1,RPSA(Full length) SDS-PAGE
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