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Product Name
Anti-67kDa Laminin Receptor Rabbit antibody
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Description
67kDa Laminin Receptor Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human 67kDa Laminin Receptor
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
ICC/IF: 1/50
FC: 1/20
IP: 1/20
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Validations
Western blot detection of 67kDa Laminin Receptor in K562,C6,3T3,Hela cell lysates using 67kDa Laminin Receptor Rabbit pAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:40kDa.
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Background
Swiss-Prot Acc.P08865.Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"