Human ITGA5/FNRA (His tag) recombinant protein

Human ITGA5/FNRA (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.

integrin subunit alpha 5(ITGA5)

FNRA

P08648

Human Cells

A DNA sequence encoding the Human ITGA5/FNRA Phe42-Tyr995 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.