Human IDH1/PICD (His tag) recombinant protein

Cat.#: 518330

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Product Information

  • Product Name
    Human IDH1/PICD (His tag) recombinant protein
  • Documents
  • Description
    Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the α-hydroxylation of phytanic acid.
  • Protein name
    isocitrate dehydrogenase (NADP(+)) 1, cytosolic(IDH1)
  • Protein short names
    PICD
  • Uniprot ID
    O75874
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human IDH1/PICD Met1-Leu414 is expressed with a 8His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human IDH1/PICD (His tag) recombinant protein

    Human IDH1/PICD (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"