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Product Name
Human IDH1/PICD (His tag) recombinant protein
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Description
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the α-hydroxylation of phytanic acid.
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Protein name
isocitrate dehydrogenase (NADP(+)) 1, cytosolic(IDH1)
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Protein short names
PICD
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Uniprot ID
O75874
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human IDH1/PICD Met1-Leu414 is expressed with a 8His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human IDH1/PICD (His tag) recombinant protein
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